We round up all the key facts and figures ahead of the 50th competitive meeting between the Wolves and Leverkusen.
Only five clubs have been ever-present in the top flight since the Wolves’ promotion to the Bundesliga in 1997: Bayern Munich, Borussia Dortmund, Werder Bremen, Schalke – and Bayer Leverkusen.
Bayer have their noses in front in the head-to-head stakes, with 23 victories to VfL’s 19. There have also been seven draws between the two teams.
None of the previous 49 meetings between the sides have finished goalless.
The Green-and-Whites have kicked off the last three seasons on home soil. A 3-0 reverse at Dortmund in 2017/18 was followed by 2-1 victories against Schalke (2018/19) and 1. FC Köln (2019/20).
Since their promotion to the top flight, VfL have only started their league campaign on a Sunday on two occasions. They shared a goalless draw with Hertha Berlin in 2006/07 before beating Eintracht Frankfurt 2-1 in 2015/16.
This is the third time VfL have faced Leverkusen on Matchday 1. The Wolves lost 2-0 at the Ulrich-Haberland-Stadion in 2000/01 before falling to a 2-1 defeat 12 months later.